The present study was based on Diabetes, its cure & herbal products available in market. Diabetes mellitus is the most common endocrine disorder, affecting 16 million individuals in the United States and 200 million worldwide. Despite the use of advanced synthetic drugs for the treatment, use of herbal remedies is gaining higher importance because of synthetic drugs have drawbacks and limitati...
Misfolding of some proteins, their self-assembly into insoluble amyloid structures underlies many diseases, constituting a group of amyloid-related pathology. Fibrillation of peptide hormone of pancreas, amylin, is considered as one of the causes of death of β-cells in type 2 diabetes. In this work we studied in vitro protection of islet β-cells from death in the presence of aggregated amylin by...
Rapid industrialization and modernization have introduced substantial amounts of toxic heavy metals into the aquatic and terrestrial environment which possess a serious threat to the flora and fauna. In recent years, considerable research work has been done and is currently underway on a number of natural biopolymers and their modifications to remove different kinds of heavy metal ions. Chitosan a...
Sweet violet also known as the Viola odorata, blooms in continental climate conditions in early spring with delicate flowers of attractive scent. It has been traditionally the part of various indigenous preparations and being used to cure respiratory and inflammatory conditions. Present review article is an attempt to cover recent developments in phytochemical and pharmacological potential of drug...
Vitamin C, also known as ascorbic acid, is a water-soluble antioxidant Vitamin having important nutritional and health benefits. Adequate consumption of fruits, vegetables and their juices with high Vitamin C content and antioxidant capacity result in improved health, reduced risk of chronic diseases, optimal nutrition and general well-being. Thus, it is essential that Vitamin C content in food it...
The proliferation of β-cells is a main contributor tothe cell mass maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of pancreas, amylin, has been proved. The in vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work the deve...
PHARMACOGNOSTIC AND PRELIMINARY PHYSIOCHEMICAL INVESTIGATIONS OF PLANT THEVETIA PERUVIANA LEAVES AND FLOWERS
Thevetia peruviana are found distributed throughout tropical parts of India. Their leaves are used as cardiotonic and diuretic. Flowers of Plant Thevetia peruviana were reported to possess good medicinal value in traditional system of medicine, the present investigation deals with Macroscopic, Microscopic and preliminary phytochemical investigation of flowers of Thevetia peruviana which includes p...
MEDICINAL EFFECT OF KAMEELA AND AMRAZE JILDIYA (SKIN DISEASES) DESCRIBED IN UNANI SYSTEM OF MEDICINE AND CURRENT RESEARCH – AN OVERVIEW
Kameela or Kamala is a well known Unani drug which is being used as medicament from centuries for the treatment of Amraze Jildiya (skin disease) by Unani Physicians and also mentioned their medicinal efficacy in Unani Classical text. It is widely scattered perennial shrub or small tree in tropical and subtropical region regions with an altitude below the 1,000 m and is description to have broad ...
Background: Gilbert’s Syndrome (GS) is the most common form of congenital, non haemolytic, mild Unconjugated Hyperbilirubinaemia. Familial cases linked with mutation in enzyme UDP glucoronosyl transferase 1producing decreased conjugation of bilirubin which accumulates in the form of unconjugated bilirubin. Hyperbilirubinaemia is mild (<6 mg/dl) while liver enzymes & histology are always f...
IN-VITRO, EX-VIVO SKIN PERMEATION AND BIOLOGICAL EVALUATION OF 18-β-GLYCYRRHITIC ACID TRANSDERMAL PATCHES
Objective: Transdermal patch is a promising approach that allows continuous input of drugs with short biological half-lives. 18 β-Glycyrrhitic acid (GA) is chemically pentacyclic triterpenoid which possess powerful anti-inflammatory action. The present study was designed to formulate GA reservoir-type transdermal patches using piperine as bioenhancer. Method: Transdermal Patch of GA was prepared ...