Rapid industrialization and modernization have introduced substantial amounts of toxic heavy metals into the aquatic and terrestrial environment which possess a severe threat to flora and fauna. In recent years, considerable research work has been done and is currently underway on some natural biopolymers and their modifications to remove different kinds of heavy metal ions. Chitosan and cellulose...
DICHLORVOS INDUCED NEPHROTOXICITY IN RAT KIDNEY: PROTECTIVE EFFECTS OF ALSTONIA BOONEI STEM BARK EXTRACT
Purpose: Dichlorvos (DDVP) causes toxicity in animals including humans. Alstonia boonei stem bark is widely used as a culinary medicine in the Ayurvedic system of medicine, possessing a number of pharmacological properties. This study was designed to evaluate the effect of Alstonia boonei (AB) against dichlorvos induced nephrotoxicity in Wistar rats. Methods: Dichlorvos (50 mg/kg body weight) was ...
Moringa oleifera can grow well in the humid tropics or hot, dry lands, can survive destitute soils, and is little affected by drought. It tolerates a wide range of rainfall with minimum annual rainfall requirements estimated at 250 mm and maximum at over 3000 mm and a pH of 5.0-9.0. Moringa leaves have been reported to be a rich source of β-carotene, protein, vitamin C, calcium and potassium and ...
Kidney stones are a growing global problem. It is also known as Urolithiasis. Lithiasis is a condition where urinary calculus is formed in the kidney and urinary tract. It is a complicated urinary disorder that has gravely troubled the health and quality of human life. Urinary stones affect 10-12% of the population in industrialized countries. There are only a few geographical areas in which the s...
ANTI-HYPERGLYCEMIC PLANTS USED BY THE TRADITIONAL HEALER OF WEST GODAVARI DISTRICT, ANDHRA PRADESH, INDIA
A survey was conducted to collect information about the effective medicinal plants used by the Traditional healer to treat diabetes. The use of herbal drugs increased worldwide because of the lack of side effects and efficacy. Traditional healing is practicing throughout the world to treat several diseases. Glycemic disease has become a severe issue in India and all over the world. The traditional...
TRADITIONAL MEDICINAL USES, PHYTOCHEMICAL PROFILE AND PHARMACOLOGICAL ACTIVITIES OF LUFFA ACUTANGULA LINN.
Inflammation is a body defence reaction to prevent the spread of injurious agent and to remove the necrosed cells and tissues. Inflammatory abnormalities are a large group of disorders which underlie a vast variety of human diseases. During treatment of inflammatory diseases, many conventional therapies (non-steroidal anti-inflammatory drugs) used to relief pain and inflammation. Continuous use of...
PROFILING OF THE CHEMICAL COMPOUNDS IN ETHYL ACETATE EXTRACTS OF LAUNAEA CORNUTA ASTERACEAE BY GC-MS
Launea cornuta Asteraceae is widely used among African communities for its medicinal and nutritional values and livestock fodder. Traditionally, it is used by Kenyan communities to manage diabetes mellitus, syphilis, and stomachache, among many other diseases. The current study profiled the organic chemical compounds in the ethyl acetate extracts of L. cornuta. Chemical compounds were identified u...
Medicinal plants are bioresources harnessed by humans to combat diseases and maintain healthy life. Plants remain the basis for development of modern drugs for the preservation of health. Garcinia kola is considered a “wonder plant” because every part of it has been found to be of medicinal importance. G. kola seed is used as an antipyretic agent in indigenous sys...
Misfolding of some proteins, their self-assembly into insoluble amyloid structures underlies many diseases, constituting a group of amyloid-related pathology. Fibrillation of peptide hormone of the pancreas, amylin, is considered as one of the causes of death of β-cells in type 2 diabetes. In this work we studied in-vitro protection of islet β-cells from death in the presence of aggregated amyli...
Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally, they hav...