Volume 4 (2017) - Issue 7, July
Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases; they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is...
DIOSPYROS MELANOXYLON ROXB IN CANCER PREVENTION: PHARMACOLOGICAL SCREENING, PHARMACOKINETICS AND CLINICAL STUDIES
Plants contain a galaxy of phytoconstituents which accounts for their remedial worth. This plant has been used expansively for its medicinal value all over the world. Different plant parts have been used for its different pharmacological screening, including cancer therapy and leaves can be wrapped to create the “beedi” filled with tobacco which has outsold conventional cigarettes in India. Ex...
MORPHOLOGICAL AND MICROSCOPIC ANALYSIS OF FIVE CURCUMA SPECIES GROWN IN SRI LANKA USING MULTIVARIATE TEST
Curcuma is an important genus used in Traditional Medicine in the world. Due to similar morphological characters and same Sinhalese vernacular names of Curcuma species, adulteration or substitution takes place. Current study was conducted to understand the similarities in morphological and microscopic characters by analyzing data using multivariate test on five species available in Sri Lanka; C. a...
CADMIUM CHLORIDE INDUCED ELECTROLYTE IMBALANCE, PANCYTOPENIA, OXIDATIVE STRESS AND RENAL DAMAGE: AMELIORATING EFFECTS OF AQUEOUS EXTRACT OF TELFAIRIA OCCIDENTALIS
Cadmium is a known nephrotoxic metal with other toxicities including pancytopenia. Telfairia occidentalis is a medicinal plant with antioxidant and heamoprotective properties. This study was carried out to investigate the ameliorating effects of aqueous extract of Telfairia occidentalison cadmium chloride-induced oxidative stress, renal damage and haematological alterations in rats. Twenty four (2...
BIOLOGICAL EVALUATION OF IN VIVO DIURETIC AND ANTIUROLITHIATIC ACTIVITIES OF LEAF EXTRACTS OF MELOCHIA CORCHORIFOLIA
The present study was investigated to establish the diuretic and antiurolithiatic activities of chloroform and ethanolic leaf extract of Melochia corchorifolia. The chloroform and ethanolic leaf extract were administered to experimental rats orally at a dose of 200 mg/ kg and 400 mg/kg. Furosemide (5 mg/kg) was used as reference standard for diuretic activity. The parameters measured for diuretic ...
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It i...