Volume 1 (2014) - Issue 7, July
Proper and normal functioning of the bodily process must be ensured in order to maintain perfect health. Any disturbance in the normal humoral balances whether it is excess, diminution or blockage leads to disease stated Avicenna (980-1037 A.D) the revered Greco Arabic physician and author of world-renowned treatise “Al Qanoon fit tib.” He has treated certain diseases by regulating metabolic p...
Traditional herbal medicines include herbs, herbal materials, herbal preparations and finished herbal products that contain active ingredients parts of plants, or other plant materials, or combinations. Clinical trials of traditional herbal medicines are carried out with herbal preparations only after standardization and identification of markers to ensure that the substances being evaluated are a...
The genus Trichosanthes L. of the family Cucurbitaceae is an annual or perennial herb distributed in tropical Asia and Australia. Pointed gourd (Trichosanthes dioica Roxb.) is known by a common name of parwal and is cultivated mainly as a vegetable. The herb has been used for overcoming problems like constipation, fever, skin infection, wounds, etc. According to Ayurveda, leaves of the plant are ...
DICHLORVOS INDUCED NEPHROTOXICITY IN RAT KIDNEY: PROTECTIVE EFFECTS OF ALSTONIA BOONEI STEM BARK EXTRACT
Purpose: Dichlorvos (DDVP) causes toxicity in animals including humans. Alstonia boonei stem bark is widely used as a culinary medicine in the Ayurvedic system of medicine, possessing a number of pharmacological properties. This study was designed to evaluate the effect of Alstonia boonei (AB) against dichlorvos induced nephrotoxicity in Wistar rats. Methods: Dichlorvos (50 mg/kg body weight) was ...
ASSESSMENT OF ANTIOXIDANT, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ETHANOL EXTRACT OF LEAVES OF CROTALARIA PALLIDA (AITON)
The ethanol leaves extract of Crotalaria pallida (Aiton) was evaluated to investigate the Phytochemical nature and some selected pharmacological activities. The plant extract indicated the presence of combined reducing sugar, tannins, flavonoids, glycosides, alkaloids and steroids. The extract showed free radical scavenging activity with an IC50 value of 37.60 µg/ml, and standard ascorbic acid sh...
Antiseptics and Disinfectants are extensively used in the health care industry and also equally in personal hygiene. Among the chemicals, silver has long been known to have antimicrobial activity. Development of new, effective and low-cost antimicrobial textiles has been an objective of this research work due to increasing resistance of microbial pathogens to traditional chemicals. The potential e...
ANTIDIARRHEAL, ANTIDIABETIC, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF METHANOLIC EXTRACTS OF LEAVES OF CLERODENDRUM VISCOSUM (VENT.)
The present study was aimed to investigate the possible antidiarrheal, antidiabetic, antioxidant and antimicrobial activity of methanolic extracts of leaves of Clerodendrum viscosum (Vent.) Different screening models are employed for an investigation like Castor oil induced diarrheal model for antidiarrheal activity screening, alloxan-induced diabetic model for antidiabetic activity screening, ant...
EFFECTIVITY OF STARVATION ON DIGESTIVE ENZYME OF FEMALE HOLOTRICHIA SERRATA (FAB) (COLEOPTERA: SCARABAEIDAE)
The effect of starvation on the digestive enzymes of female Holotrichia serrata (Fab) shows that there are considerable general reductions in enzymatic activities except in a lipase in both gut sections; however there are considerable increases of soluble proteins, both the gut section homogenates of the starved female. The maximum reduction of protease is 83% in a hindgut and 86% in the midgut fo...
HUMAN GLUTATHIONE S-TRANSFERASE A1-1 BINDING WITH NATURALLY OCCURRING LIGANDS: ASSESSMENT BY DOCKING SIMULATIONS
Glutathione S-transferases are phase-II enzymes associated with detoxification and resistance to drugs and xenobiotics. The majority of human tumors and human tumor cell lines express significant amounts of alpha class Glutathione S-Transferase A1-1. Present study aimed to examine hGSTA1-1 interaction with some naturally occurring ligands using docking simulations. Docking simulation using Glutath...
PRELIMINARY PHYTOCHEMICAL SCREENING AND QUANTIFICATION OF BIOACTIVE COMPOUNDS IN THE LEAVES OF SPINACH (SPINACEAE OLERACEAE L.)
Plants are the sources for a large number of secondary metabolites. Spinacia oleraceae is a green leafy vegetable belonging to Chenopodiaceae family. It is having medicinal properties due to rich nutritional value and is extremely rich in antioxidants. Antioxidant property of the spinach is due to the presence of bioactive compounds. The present study aims to screen the phytochemicals of different...